Dr. Laura Fuhr

Field of research

  • Physiologically based pharmacokinetic (PBPK) Modeling of drug profiles and interactions                          

Curriculum vitae

Since 09/2024: Postdoctoral researcher Clinical Pharmacy, Saarland University, Saarbrücken

04/2019 - 09/2024: Doctoral student Clinical Pharmacy, Saarland University, Saarbrücken

12/2018 - 03/2019: Research assistant Clinical Pharmacy, Saarland University, Saarbrücken

12/2018: Licensed as pharmacist

05/2018 - 10/2018: Practical year, Apotheke am Dudoplatz, Saarbrücken

11/2017 - 04/2018: Practical year and diploma student Clinical Pharmacy, Saarland University, Saarbrücken

10/2013 - 10/2017: Pharmacy studies, Saarland University, Saarbrücken

06/2013: Abitur, Albertus-Magnus-Gymnasium, Sankt Ingbert

Publications

Manuscripts

Kovar C, Loer HLH, Rüdesheim S, Fuhr LM, Marok FZ, Selzer D, Schwab M, Lehr T. A physiologically-based pharmacokinetic precision dosing approach to manage dasatinib drug-drug interactions. CPT Pharmacometrics Syst Pharmacol. 2024. doi:10.1002/psp4.13146

Loer HLH, Kovar C, Rüdesheim S, Marok FZ, Fuhr LM, Selzer D, Schwab M, Lehr T. Physiologically based pharmacokinetic modeling of imatinib and N-desmethyl imatinib for drug-drug interaction predictions. CPT Pharmacometrics Syst Pharmacol. 2024;00:1-15.

Fuhr LM, Marok FZ, Fuhr U, Selzer D, Lehr T. Physiologically based pharmacokinetic modeling of bergamottin and 6,7-dihydroxybergamottin to describe CYP3A4 mediated grapefruit-drug interactions. Clin Pharmacol Ther. 2023;114(2):470-482.

Marok FZ, Wojtyniak J-G, Fuhr LM, Selzer D, Schwab M, Weiss J, Haefeli WE, Lehr T. A physiologically based pharmacokinetic model of ketoconazole and its metabolites as drug–drug interaction perpetrators. Pharmaceutics. 2023;15(2):679.

Fuhr LM, Marok FZ, Mees M, Mahfoud F, Selzer D, Lehr T. A physiologically based pharmacokinetic and pharmacodynamic model of the CYP3A4 substrate felodipine for drug-drug interaction modeling. Pharmaceutics 2022;14(7):1474.

Türk D, Fuhr LM, Marok FZ, Rüdesheim S, Kühn A, Selzer D, Schwab M, Lehr T. Novel models for the prediction of drug-gene interactions. Expert Opin on Drug Metab Toxicol 2021;17(11):1293-1310.

Marok FZ, Fuhr LM, Hanke N, Selzer D, Lehr T. Physiologically based pharmacokinetic modeling of bupropion and its metabolites in a CYP2B6 drug-drug-gene interaction network. Pharmaceutics 2021;13(3):331.

Fuhr LM, Marok FZ, Hanke N, Selzer D, Lehr T. Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and its drug-drug interaction potential: a physiologically based pharmacokinetic modeling approach. Pharmaceutics 2021;13(2):270.

Fuhr LM, Hanke N, Meibohm B, Lehr T. Effective removal of dabigatran by idarucizumab or hemodialysis: a physiologically based pharmacokinetic modeling analysis. Clin Pharmacokinet 2020;59(6):809-825.

Contact information

Dr. Laura Fuhr

Clinical Pharmacy
Saarland University
Campus C4 1, Room -1.08
66123 Saarbrücken

T: +49/681/302-70254
F: +49/681/302-70258

laura.fuhr[at]uni-saarland.de