Senior Professor for Genetics and Epigenetics
Our research group focuses on the investigation of epigenetic phenomena associated with development and disease. The following research areas are of particular interest: Characterization and functional analysis of imprinted genes, Epigenetic mapping of genomes (Epigenomics), Research into epigenetic programs in stem cells, Evolution of epigenetic mechanisms. We use and develop state-of-the-art molecular methods and bioinformatic data analysis pipelines and we produce large molecular data sets in our own Sequencing Facility. As coodinator of the German Epigenome Program we significantly contributed to the first epigenetic atlas of all human cell types. We are member of the International Human Epigenome Consortium.
Arbeitsgruppe
Now available !!! The new AvitiTM Genome Sequencer has arrived at the Epigenomics Sequencing Facility !
We are pleased to announce that the AvitiTM platform (Element Biosc.) is now ready to use for internal and external users.
Please find more information about the AvitiTM and NGS applications on the Epigenomics Sequencing Facility web site.
In the latest episode of the science podcast "The Code of Life" (available only in German) published by the German Human Genome-Phenome Archive (GHGA), Prof. Dr. Melanie Brinkmann (TU/HZI Braunschweig) and Prof. Dr. Adam Grundhoff (Leibniz Institute for Virology, Hamburg) dive into the fascinating topic of viral DNA in humans.
They explore how viruses not only cause diseases but have also profoundly shaped and influenced our genetic makeup.
The podcast and further information are available here.
Why are metadata important for research and data analysis? Which genomic data portals are out there and what do we need from them? How do we make our research data FAIR? These questions will be addressed in an upcoming webinar by Anandhi Iyappan (EMBL Heidelberg) and Karoline Mauer (DZNE Bonn).
The webinar will take place on September 26, 2024, 16:00 CEST ((replacing the webinar that was postponed in June) and will be available on demand afterwards. It is part of a training series by the German Human Genome-Phenome Archive (GHGA).
Please find more information here.
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