Publications

2024
  • Diebolt CM, Schaudien D, Junker K, Krasteva-Christ G, Tschernig T, Englisch CN. New insights in the renal distribution profile of TRPC3 - Of mice and men. Ann Anat. 2024. 252:152192. doi: 10.1016/j.aanat.2023.152192. PMID: 37977270.
  • Schlüter AM*, Redl K*, Tschernig T, Maxeiner S#, and Krasteva-Christ G#. Rare Superior and Middle Trunk Fusion Accompanied by Altered Division Rearrangement Results in a Unique Brachial Plexus Variant: A Case Report. Diagnostics. 2024. 14:1239. doi.org/10.3390/diagnostics14121239. PMID: 38928654* shared first authorship/# shared last authorship
  • Zahnow F, Jäger C*, Mohamed Y*, Vogelhuber G*, May F, Ciocan AM, Manieri A, Maxeiner S, Krasteva-Christ S, Cobain MRD, Podsiadlowski L, Crespo-Picazo JL, García-Párraga D, Althaus M. The evolutionary path of the epithelial sodium channel δ-subunit in Cetartiodactyla points to a role in sodium sensing. BioRxive 2024. https://doi.org/10.1101/2024.11.18.623996 * shared first authorship
  • Kern F, Wagner V, Wahl V, Ludwig N, Graf S, Amand J, Foltz A, Atkins M, Kedir B, Hadjilaou A, Flotho M, Grandke F, Wartenberg P, Hollenhorst MI, Lotter H, Müller R, Boehm U, Hahn O, Jacobs T, Krasteva-Christ G, Wyss-Coray T, Keller A. Spatiotemporal transcriptomic niches of complement pathway and serine protease inhibitor activation in aging and infection. BioRxive 2024. https://doi.org//10.1101/2024.11.04.621811
2023
  • Hollenhorst MI*, Husnik T*, Zylka M, Duda N, Flockerzi V, Tschernig T, Maxeiner S*, Krasteva-Christ G*. Human tracheal brush cells are cholinergic and influence mucociliary clearance. Respir Res. 2023. 24(1):267. doi: 10.1186/s12931-023-02570-8. PMID: 37925434
  • Shah DS, Nisr RB, Krasteva-Christ G, Hundal HS. Caveolin-3 loss linked with the P104L LGMD-1C mutation modulates skeletal muscle mTORC1 signalling and cholesterol homeostasis. J Cachexia Sarcopenia Muscle. 2023 Sep 6. doi: 10.1002/jcsm.13317. PMID: 37671684.
  • Englisch CN, Wadood NA, Pätzold L, Gallagher A, Krasteva-Christ G, Becker SL, Bischoff M. Establishing an experimental Pseudomonas aeruginosa keratitis model in mice - Challenges and solutions. Ann Anat. 2023 Aug;249:152099. doi: 10.1016/j.aanat.2023.152099. PMID: 37105406.
  • Hollenhorst MI, Krasteva-Christ G. Chemosensory cells in the respiratory tract as crucial regulators of innate immune responses. J Physiol. 2023 May;601(9):1555-1572. doi: 10.1113/JP282307. PMID: 37009787.
  • Maxeiner S, Krasteva-Christ G, Althaus M. Pitfalls of using sequence databases for heterologous expression studies - a technical review. J Physiol. 2023 May;601(9):1611-1623. doi: 10.1113/JP284066. PMID: 36762618.
2022
  • Ahmad-Mansour N, Elhawy MI, Huc-Brandt S, Youssouf N, Pätzold L, Martin M, Abdel-Wadood N, Aljohmani A, Morsli M, Krasteva-Christ G, Becker SL, Yildiz D, Lavigne JP, Gannoun-Zaki L, Bischoff M, Molle V. Characterization of the Secreted Acid Phosphatase SapS Reveals a Novel Virulence Factor ofStaphylococcus aureus That Contributes to Survival and Virulence in Mice. Int J Mol Sci. 2022 Nov 14;23(22):14031. doi: 10.3390/ijms232214031. PMID: 36430506
  • Benthien H, Fresenborg B, Pätzold L, Elhawy MI, Huc-Brandt S, Beisswenger C, Krasteva-Christ G, Becker SL, Molle V, Knobloch JK, Bischoff M. The Transcription Factor SpoVG Is of Major Importance for Biofilm Formation of Staphylococcus epidermidis under In Vitro Conditions, but Dispensable for In Vivo Biofilm Formation. Int J Mol Sci. 2022 Mar 17;23(6):3255. doi: 10.3390/ijms23063255. PMID: 35328675
  • Hollenhorst MI*, Nandigama R*, Evers SB*, Gamayun I, Abdel Wadood N, Salah A, Pieper M, Wyatt A, Stukalov A, Gebhardt A, Nadolni W, Burow W, Herr C, Beisswenger C, Kusumakshi S, Ectors F, Kichko TI, Hübner L, Reeh P, Munder A, Wienhold SM, Witzenrath M, Bals R, Flockerzi V, Gudermann T, Bischoff M, Lipp P, Zierler S, Chubanov V, Pichlmair A, König P, Boehm U, Krasteva-Christ G. Bitter taste signaling in tracheal epithelial brush cells elicits innate immune responses to bacterial infection. J Clin Invest. 2022 Jul 1;132(13):e150951. doi: 10.1172/JCI150951. PMID: 35503420 *Contributed equally
  • Hollenhorst MI*, Kumar P*, Zimmer M, Salah A, Maxeiner S, Elhawy MI, Evers SB, Flockerzi V, Gudermann T, Chubanov V, Boehm U, Krasteva-Christ G. Taste Receptor Activation in Tracheal Brush Cells by Denatonium Modulates ENaC Channels via Ca2+, cAMP and ACh. Cells. 2022 Aug 4;11(15):2411. doi: 10.3390/cells11152411. PMID: 35954259 *Contributed equally
  • Maxeiner S, Benseler F, Brose N, Krasteva-Christ G. Of Humans and Gerbils- Independent Diversification of Neuroligin-4 Into X- and Y-Specific Genes in Primates and Rodents. Front Mol Neurosci. 2022 Mar 30;15:838262. doi: 10.3389/fnmol.2022.838262. PMID: 35431802
  • Maxeiner S, Tschernig T, Brenner E. Editorial. Vertebrates Diversity. Ann Anat. 2022 Aug;243:151947. doi: 10.1016/j.aanat.2022.151947. Epub 2022 Apr 22. PMID: 35470052
  • Shankhwar S, Schwarz K, Katiyar R, Jung M, Maxeiner S, Südhof TC, Schmitz F. RIBEYE B-Domain Is Essential for RIBEYE A-Domain Stability and Assembly of Synaptic Ribbons. Front Mol Neurosci. 2022 Jan 28;15:838311. doi: 10.3389/fnmol.2022.838311. PMID: 35153673
  • Suiwal S, Dembla M, Schwarz K, Katiyar R, Jung M, Carius Y, Maxeiner S, Lauterbach MA, Lancaster CRD, Schmitz F. Ciliary Proteins Repurposed by the Synaptic Ribbon: Trafficking Myristoylated Proteins at Rod Photoreceptor Synapses. Int J Mol Sci. 2022 Jun 27;23(13):7135. doi: 10.3390/ijms23137135. PMID: 35806143
  • Wartenberg P, Lux F, Busch K, Fecher-Trost C, Flockerzi V, Krasteva-Christ G, Boehm U, Weissgerber P. Additional data for the mouse TRPV6 expression atlas. Data Brief. 2022 Apr 22;42:108201. doi: 10.1016/j.dib.2022.108201. PMID: 35516004
  • Wartenberg P, Lux F, Busch K, Fecher-Trost C, Wyatt A, Flockerzi V, Krasteva-Christ G, Boehm U, Weissgerber P. Combining mass spectrometry and genetic labeling in mice to report TRP channel expression. MethodsX. 2021 Dec 14;9:101604. doi: 10.1016/j.mex.2021.101604. PMID: 36569450
2021
  • Gawlitza J, Steinhäuser J, Bücker A, Krasteva-Christ G, Tschernig T. Time is bone - Quantitative comparison of decalcification solvents in human femur samples using dual-X-ray-absorptiometry and computed tomography. Ann Anat. 2021 May;235:151696. doi: 10.1016/j.aanat.2021.151696. Epub 2021 Feb 8. PMID: 33571643.
  • Gettings SM*, Maxeiner S*, Tzika M, Cobain MRD, Ruf I, Benseler F, Brose N, Krasteva-Christ G, Vande Velde G, Schönberger M, Althaus M. Two Functional Epithelial Sodium Channel Isoforms Are Present in Rodents despite Pronounced Evolutionary Pseudogenization and Exon Fusion. Mol Biol Evol. 2021 Dec 9;38(12):5704-5725. doi: 10.1093/molbev/msab271. Erratum in: Mol Biol Evol. 2022 Feb 3;39(2): PMID: 34491346 *Contributed equally
  • Hollenhorst MI, Krasteva-Christ G. Nicotinic Acetylcholine Receptors in the Respiratory Tract. Molecules. 2021 Oct 9;26(20):6097. doi: 10.3390/molecules26206097. PMID: 34684676
  • Maxeiner S, Gebhardt S*, Schweizer F*, Venghaus AE*, Krasteva-Christ G. Of mice and men - and guinea pigs? Ann Anat. 2021 Nov;238:151765. doi: 10.1016/j.aanat.2021.151765. Epub 2021 May 14. PMID: 34000371 *Contributed equally
  • Wartenberg P, Lux F, Busch K, Fecher-Trost C, Flockerzi V, Krasteva-Christ G, Boehm U, Weissgerber P. A TRPV6 expression atlas for the mouse. Cell Calcium. 2021 Dec;100:102481. doi: 10.1016/j.ceca.2021.102481. Epub 2021 Oct 1. PMID: 34628109
2020
  • Kumar P, Scholze P, Fronius M, Krasteva-Christ G*, Hollenhorst MI.* Nicotine stimulates ion transport via metabotropic β4 subunit containing nicotinic ACh receptors. Br J Pharmacol. 2020 Dec;177(24):5595-5608. doi: 10.1111/bph.15270. PMID: 32959891 *Contributed equally
  • Weber J, Rajan S, Schremmer C, Chao YK, Krasteva-Christ G, Kannler M, Yildirim AÖ, Brosien M, Schredelseker J, Weissmann N, Grimm C, Gudermann T, Dietrich A. TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema. JCI Insight. 2020 Oct 15;5(20):e134464. doi: 10.1172/jci.insight.134464. PMID: 32931478
  • Fairless R, Williams SK, Katiyar R, Maxeiner S, Schmitz F, Diem R. ERG Responses in Mice with Deletion of the Synaptic Ribbon Component RIBEYE. Invest Ophthalmol Vis Sci. 2020 May 11;61(5):37. doi: 10.1167/iovs.61.5.37. PMID: 32437548
  • Perniss A, Latz A, Boseva I, Papadakis T, Dames C, Meisel C, Meisel A, Scholze P, Kummer W, Krasteva-Christ G. Acute nicotine administration stimulates ciliary activity via α3β4 nAChR in the mouse trachea. Int Immunopharmacol. 2020 Jul;84:106496. doi: 10.1016/j.intimp.2020.106496. PMID: 32304995
  • Dembla E, Dembla M, Maxeiner S, Schmitz F. Synaptic ribbons foster active zone stability and illumination-dependent active zone enrichment of RIM2 and Cav1.4 in photoreceptor synapses. Sci Rep. 2020 Apr 6;10(1):5957. doi: 10.1038/s41598-020-62734-0. PMID: 32249787
  • Shah DS, Nisr RB, Stretton C, Krasteva-Christ G, Hundal HS. Caveolin-3 deficiency associated with the dystrophy P104L mutation impairs skeletal muscle mitochondrial form and function. J Cachexia Sarcopenia Muscle. 2020 Jun;11(3):838-858. doi: 10.1002/jcsm.12541. PMID: 32090499
  • Maxeiner S*, Benseler F*, Krasteva-Christ G, Brose N, Südhof TC. Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents. Mol Biol Evol. 2020 May 1;37(5):1243-1258. doi: 10.1093/molbev/msaa014. PMID: 32011705 *Contributed equally
  • Hollenhorst MI*, Jurastow I*, Nandigama R*, Appenzeller S, Li L, Vogel J, Wiederhold S, Althaus M, Empting M, Altmüller J, Hirsch AKH, Flockerzi V, Canning BJ, Saliba AE, Krasteva-Christ G. Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling. FASEB J. 2020 Jan;34(1):316-332. doi: 10.1096/fj.201901314RR. PMID: 31914675 *Contributed equally
2019
  • Maxeiner S, Sester M, Krasteva-Christ G. Novel human sex-typing strategies based on the autism candidate gene NLGN4X and its male-specific gametologue NLGN4Y. Biol Sex Differ. 2019 Dec 18;10(1):62. doi: 10.1186/s13293-019-0279-x. PMID: 31852540
  • Zaffalon S, Latz A, Krasteva-Christ G, Maxeiner S. Sex identification in horses (Equus caballus) based on the gene pair NLGN4X/NLGN4Y. Anim Genet. 2019 Oct;50(5):551. doi: 10.1111/age.12823. PMID: 31318073
  • Trotter JH, Hao J, Maxeiner S, Tsetsenis T, Liu Z, Zhuang X, Südhof TC. Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters. J Cell Biol. 2019 Aug 5;218(8):2677-2698. doi: 10.1083/jcb.201812076. PMID: 31262725
  • Wichmann L, Dulai JS, Marles-Wright J, Maxeiner S, Szczesniak PP, Manzini I, Althaus M. An extracellular acidic cleft confers profound H+-sensitivity to epithelial sodium channels containing the δ-subunit in Xenopus laevis. J Biol Chem. 2019 Aug 16;294(33):12507-12520. doi: 10.1074/jbc.RA119.008255. PMID: 31248986
  • Zakrzewicz A, Richter K, Zakrzewicz D, Siebers K, Damm J, Agné A, Hecker A, McIntosh JM, Chamulitrat W, Krasteva-Christ G, Manzini I, Tikkanen R, Padberg W, Janciauskiene S, Grau V. SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player. Front Immunol. 2019 Apr 4;10:664. doi: 10.3389/fimmu.2019.00664. PMID: 31019507
  • Baumann L, Kauschke V, Vikman A, Dürselen L, Krasteva-Christ G, Kampschulte M, Heiss C, Yee KT, Vetter DE, Lips KS. Deletion of nicotinic acetylcholine receptor alpha9 in mice resulted in altered bone structure. Bone. 2019 Mar;120:285-296. doi: 10.1016/j.bone.2018.11.003. PMID: 30414510
  • Scherer JJ, Reichrath S, Tschernig T, Maxeiner S. A snapshot of anatomy teaching: Peer-led anatomy boot camps - Priming for success? Ann Anat. 2019 Jan;221:141-147. doi: 10.1016/j.aanat.2018.10.005. PMID: 30326262
  • Hamza A, Radosa J, Meyberg-Solomayer G, Solomayer EF, Takacs Z, Juhasz-Boess I, Krasteva-Christ G, Tschernig T, Maxeiner S. Trial integration of combined ultrasound and laparoscopy tuition in an undergraduate anatomy class with volunteer participation - A pilot study. Ann Anat. 2019 Jan;221:101-107. doi: 10.1016/j.aanat.2018.09.009. PMID: 30300688
2018
  • Nassenstein C, Krasteva-Christ G, Renz H. New aspects of neuroinflammation and neuroimmune crosstalk in the airways. J Allergy Clin Immunol. 2018 Nov;142(5):1415-1422. doi: 10.1016/j.jaci.2018.09.011. PMID: 30409249
  • Keshavarz M, Skill M, Hollenhorst MI, Maxeiner S, Walecki M, Pfeil U, Kummer W, Krasteva-Christ G. Caveolin-3 differentially orchestrates cholinergic and serotonergic constriction of murine airways. Sci Rep. 2018 May 14;8(1):7508. doi: 10.1038/s41598-018-25445-1. PMID: 29760450
  • Ringholz FC, Higgins G, Hatton A, Sassi A, Moukachar A, Fustero-Torre C, Hollenhorst M, Sermet-Gaudelus I, Harvey BJ, McNally P, Urbach V. Resolvin D1 regulates epithelial ion transport and inflammation in cystic fibrosis airways. J Cyst Fibros. 2018 Sep;17(5):607-615. doi: 10.1016/j.jcf.2017.11.017. PMID: 29233471
  • Becker L, Schnee ME, Niwa M, Sun W, Maxeiner S, Talaei S, Kachar B, Rutherford MA, Ricci AJ. The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse. Elife. 2018 Jan 12;7:e30241. doi: 10.7554/eLife.30241. PMID: 29328021
  • Jean P*, Lopez de la Morena D*, Michanski S*, Jaime Tobón LM, Chakrabarti R, Picher MM, Neef J, Jung S, Gültas M, Maxeiner S, Neef A, Wichmann C, Strenzke N, Grabner C, Moser T. The synaptic ribbon is critical for sound encoding at high rates and with temporal precision. Elife. 2018 Jan 12;7:e29275. doi: 10.7554/eLife.29275. PMID: 29328020 *Contributed equally
2017
  • Goedicke-Fritz S, Härtel C, Krasteva-Christ G, Kopp MV, Meyer S, Zemlin M. Preterm Birth Affects the Risk of Developing Immune-Mediated Diseases. Front Immunol. 2017 Oct 9;8:1266. doi: 10.3389/fimmu.2017.01266. PMID: 29062316
  • Anderson GR*, Maxeiner S*, Sando R, Tsetsenis T, Malenka RC, Südhof TC. Postsynaptic adhesion GPCR latrophilin-2 mediates target recognition in entorhinal-hippocampal synapse assembly. J Cell Biol. 2017 Nov 6;216(11):3831-3846. doi: 10.1083/jcb.201703042. PMID: 28972101 *Contributed equally
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  • Lykhmus O, Voytenko LP, Lips KS, Bergen I, Krasteva-Christ G, Vetter DE, Kummer W, Skok M. Nicotinic Acetylcholine Receptor α9 and α10 Subunits Are Expressed in the Brain of Mice. Front Cell Neurosci. 2017 Sep 12;11:282. doi: 10.3389/fncel.2017.00282. PMID: 28955208
  • Moussa AT, Rabung A, Reichrath S, Wagenpfeil S, Dinh T, Krasteva-Christ G, Meier C, Tschernig T. Modulation of macrophage phagocytosis in vitro-A role for cholinergic stimulation? Ann Anat. 2017 Nov;214:31-35. doi: 10.1016/j.aanat.2017.07.007. PMID: 28823709
  • Zakrzewicz A, Richter K, Agné A, Wilker S, Siebers K, Fink B, Krasteva-Christ G, Althaus M, Padberg W, Hone AJ, McIntosh JM, Grau V. Canonical and Novel Non- Canonical Cholinergic Agonists Inhibit ATP-Induced Release of Monocytic Interleukin-1β via Different Combinations of Nicotinic Acetylcholine Receptor Subunits α7, α9 and α10. Front Cell Neurosci. 2017 Jul 5;11:189. doi: 10.3389/fncel.2017.00189. PMID: 28725182
  • Wyatt A, Wartenberg P, Candlish M, Krasteva-Christ G, Flockerzi V, Boehm U. Genetic strategies to analyze primary TRP channel-expressing cells in mice. Cell Calcium. 2017 Nov;67:91-104. doi: 10.1016/j.ceca.2017.05.009. PMID: 28571899
  • Keshavarz M, Schwarz H, Hartmann P, Wiegand S, Skill M, Althaus M, Kummer W, Krasteva-Christ G. Caveolin-1: Functional Insights into Its Role in Muscarine- and Serotonin-Induced Smooth Muscle Constriction in Murine Airways. Front Physiol. 2017 May 15;8:295. doi: 10.3389/fphys.2017.00295. PMID: 28555112
  • Lee SJ, Wei M, Zhang C, Maxeiner S, Pak C, Calado Botelho S, Trotter J, Sterky FH, Südhof TC. Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses. J Neurosci. 2017 Feb 1;37(5):1062-1080. doi: 10.1523/JNEUROSCI.2768-16.2016. PMID: 27986928
< 2017

Publications prior to 2017 of the following lab members are linked to PubMed directly:

Univ.-Prof. Gabriela Krasteva-Christ

Dr. rer. nat. Monika Hollenhorst

Dr. rer. nat. Stephan Maxeiner