Selected Publications

Hielscher, F., Schmidt, T., Enders, M., Leyking, S., Gerhart, M., van Bentum, K., Mihm, J., Schub, D., Sester, U., and Sester, M. The inactivated herpes zoster vaccine HZ/su induces a varicella zoster virus specific cellular and humoral immune response in patients on dialysis. eBioMedicine 2024; 108:105335.  https://doi.org/10.1016/j.ebiom.2024.105335    Impact Punkte: 9.7.

Gardiner, B.J., Westall, G., Sester, M., Torre-Cisneros, J., and Kotton, C.N. Immune Monitoring Assays: Predicting Cytomegalovirus and Other Infections in Solid Organ Transplant Recipients. Transplantation 2024; in press. Impact Punkte: 5.3

Assmann, G., Schmidt, M., and Sester, M. Scattered pustular lesions 10 days after Shingrix vaccination in systemic sclerosis patient after successful autologous non-myeloablative haemopoietic stem-cell transplantation. BMJ Case Rep 2024; 17. https://doi.org/10.1136/bcr-2024-259620 Impact Punkte: 0.6.

Bronder, S., and Sester, M. A promising boost for the Rift Valley fever vaccine pipeline. Lancet Infect Dis 2024; doi.org/10.1016/S1473-3099(24)00428-6 Impact Punkte: 36.4.

Gärtner, B.C., and Sester, M. Virus-specific T cell efficacy after solid organ transplantation: More questions than answers. Am J Transplant 2024. https://doi.org/10.1016/j.ajt.2024.05.021 Impact Punkte: 8.9.

Fousse, M., Fassbender, K., Schunk, S.J., Schmidt, T., and Stogbauer, J. Apheresis treatment in autoimmune neurological diseases: Predictors of good clinical outcome and success of follow-up therapy with B-cell depletion.  J Neurol Sci 2024; 461:123050. https://doi.org/10.1016/j.jns.2024.123050 Impact Punkte: 4.553.

Urschel, R., Bronder, S., Klemis, V., Marx, S., Hielscher, F., Abu-Omar, A., Guckelmus, C., Schneitler, S., Baum, C., Becker, S.L., Gärtner, B.C., Sester, U., Martinez, L., Widera, M., Schmidt, T., and Sester, M. SARS-CoV-2-specific cellular and humoral immunity after bivalent BA.4/5 COVID-19-vaccination in previously infected and non-infected individuals. Nat Commun 2024; 15:3077. https://doi.org/10.1038/s41467-024-47429-8 Impact Punkte: 14.7.

Bronder, S., Mihm, J., Urschel, R., Klemis, V., Schmidt, T., Marx, S., Abu-Omar, A., Hielscher, F., Guckelmus, C., Widera, M., Sester, U., and Sester, M. Potent induction of humoral and cellular immunity after bivalent BA.4/5 mRNA vaccination in dialysis patients. NPJ Vaccines 2024; 9:25. https://doi.org/10.1038/s41541-024-00816-0 Impact Punkte: 6.9.

Ziegler, L., Klemis, V., Schmidt, T., Schneitler, S., Baum, C., Neumann, J., Becker, S.L., Gärtner, B.C., Sester, U., and Sester, M. Is ipsilateral administration of COVID-19 vaccine boosters the optimal approach?eBioMedicine 2023. https://doi.org/https://doi.org/10.1016/j.ebiom.2023.104853 Impact Punkte: 9.7.

Harries, M., Jaeger, V.K., Rodiah, I., Hassenstein, M.J., Ortmann, J., Dreier, M., von Holt, I., Brinkmann, M., Dulovic, A., Gornyk, D., Hovardovska, O., Kuczewski, C., Kurosinski, M.A., Schlotz, M., Schneiderhan-Marra, N., Strengert, M., Krause, G., Sester, M., Klein, F., Petersmann, A., Karch, A., and Lange, B. Bridging the gap - estimation of 2022/2023 SARS-CoV-2 healthcare burden in Germany based on multidimensional data from a rapid epidemic panel. Int J Infect Dis 2024; 139:50-58. https://doi.org/10.1016/j.ijid.2023.11.014 Impact Punkte: 4.8.

Ziegler, L., Klemis, V., Schmidt, T., Schneitler, S., Baum, C., Neumann, J., Becker, S.L., Gärtner, B.C., Sester, U., and Sester, M. Differences in SARS-CoV-2 specific humoral and cellular immune responses after contralateral and ipsilateral COVID-19 vaccination. EBioMedicine 2023; 95:104743. https://doi.org/10.1016/j.ebiom.2023.104743 Impact Punkte: 9.7.

Halmans, L., Venhorst, A., Klemis, V., Schmidt, T., Greiß, F., Sester, U., Gärtner, B.C., Sester, M., and Meyer, T. Immune Response to COVID-19 Vaccination in Elite Athletes. Exerc Immunol Rev 2024; in press. Impact Punkte: 7.3

Kotton, C.N., Kamar, N., Wojciechowski, D., Eder, M., Hopfer, H., Randhawa, P., Sester, M., Comoli, P., Tedesco Silva, H., Knoll, G., Brennan, D.C., Trofe-Clark, J., Pape, L., Axelrod, D., Kiberd, B., Wong, G., Hirsch, H.H., and Transplantation Society International, B.K.P.C.G. The Second International Consensus Guidelines on the Management of BK Polyomavirus in Kidney Transplantation. Transplantation 2024. https://doi.org/10.1097/TP.0000000000004976 Impact Punkte: 5.3.

Gies, S., Melchior, P., Stroeder, R., Tanzer, T., Theobald, L., Pohlers, M., Glombitza, B., Sester, M., Solomayer, E.F., and Walch-Ruckheim, B. Immune landscape of vulvar cancer patients treated with surgery and adjuvant radiotherapy revealed restricted T cell functionality and increased IL-17 expression associated with cancer relapse. Int J Cancer 2024; 154:343-358. https://doi.org/10.1002/ijc.34745 Impact Punkte: 5.7.

Kotton, C.N., Torre-Cisneros, J., Yakoub-Agha, I., and Faculty, C.M.V.I.S. Slaying the "Troll of Transplantation"-new frontiers in cytomegalovirus management. A report from the CMV International Symposium 2023. Transpl Infect Dis 2023:e14183. https://doi.org/10.1111/tid.14183 Impact Punkte: 2.6.

Mohammad, L., Fousse, M., Wenzel, G., Flotats Bastardas, M., Fassbender, K., Dillmann, U., Schick, B., Zemlin, M., Gärtner, B.C., Sester, U., Schub, D., Schmidt, T., and Sester, M. Alterations in pathogen-specific cellular and humoral immunity associated with acute peripheral facial palsy of infectious origin. J Neuroinflammation 2023; 20:246. https://doi.org/10.1186/s12974-023-02933-4 Impact Punkte: 9.3.

 Vasiliu, A., Martinez, L., Gupta, R.K., Hamada, Y., Ness, T., Kay, A., Bonnet, M., Sester, M., Kaufmann, S.H.E., Lange, C., and Mandalakas, A.M. Tuberculosis prevention: current strategies and future directions. Clin Microbiol Infect 2023. https://doi.org/10.1016/j.cmi.2023.10.023 Impact Punkte: 10.9.

Kotton, C.N., Torre-Cisneros, J., International, C.M.V.S.F., Aguado, J.M., Alain, S., Baldanti, F., Baumann, G., Boeken, U., de la Calle, M., Carbone, J., Ciceri, F., Comoli, P., Couzi, L., Danziger-Isakov, L., Fernandez-Ruiz, M., Girmenia, C., Grossi, P.A., Hirsch, H.H., Humar, A., Kamar, N., Kotton, C., Ljungman, P., Malagola, M., Mira, E., Mueller, N., Sester, M., Teng, C.J., Torre-Cisneros, J., Ussetti, P., Westall, G., Wolf, D., and Zamora, M. Cytomegalovirus in the transplant setting: Where are we now and what happens next? A report from the International CMV Symposium 2021. Transpl Infect Dis 2022; 24:e13977. https://doi.org/10.1111/tid.13977 Impact Punkte: 2.6.

Zewinger, S., Reiser, J., Jankowski, V., Alansary, D., Hahm, E., Triem, S., Klug, M., Schunk, S.J., Schmit, D., Kramann, R., Korbel, C., Ampofo, E., Laschke, M.W., Selejan, S.R., Paschen, A., Herter, T., Gaul, S., Silbernagel, G., Sester, M., Sester, U., Assmann, G., Bals, R., Kostner, G., Jahnen-Dechent, W., Menger, M.D., Rohrer, L., Marz, W., Bohm, M., Jankowski, J., Kopf, M., Latz, E., Niemeyer, B.A., Fliser, D., Laufs, U., and Speer, T. Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form. Nat Immunol 2023; 24:412-413. https://doi.org/10.1038/s41590-023-01424-1 Impact Punkte: 27.7.

Windpessl, M., Kostopoulou, M., Conway, R., Berke, I., Bruchfeld, A., Soler, M.J., Sester, M., and Kronbichler, A. Preventing infections in immunocompromised patients with kidney diseases: vaccines and antimicrobial prophylaxis. Nephrol Dial Transplant 2023; 38:ii40-ii49. doi.org/10.1093/ndt/gfad080 Impact Punkte: 4.8.

Bronder, S., and Sester, M. A novel Rift Valley fever vaccine. Lancet Infect Dis 2023; 23:887-889. doi.org/10.1016/S1473-3099(23)00134-2 Impact Punkte: 36.4.

Hamada, Y., Gupta, R.K., Quartagno, M., Izzard, A., Acuna-Villaorduna, C., Altet, N., Diel, R., Dominguez, J., Floyd, S., Gupta, A., Huerga, H., Jones-Lopez, E.C., Kinikar, A., Lange, C., van Leth, F., Liu, Q., Lu, W., Lu, P., Rueda, I.L., Martinez, L., Mbandi, S.K., Munoz, L., Padilla, E.S., Paradkar, M., Scriba, T., Sester, M., Shanaube, K., Sharma, S.K., Sloot, R., Sotgiu, G., Thiruvengadam, K., Vashishtha, R., Abubakar, I., and Rangaka, M.X. Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis. EClinicalMedicine 2023; 56:101815. doi.org/10.1016/j.eclinm.2022.101815 Impact Punkte: 9.6.

Gärtner, B.C., Klemis, V., Schmidt, T., Sester, M., and Meyer, T. Transient Positive SARS-CoV-2 PCR without Induction of Systemic Immune Responses. Vaccines (Basel) 2023; 11. doi.org/10.3390/vaccines11020482 Impact Punkte: 5.2.

Diener, C., Hart, M., Kehl, T., Becker-Dorison, A., Tanzer, T., Schub, D., Krammes, L., Sester, M., Keller, A., Unger, M., Walch-Ruckheim, B., Lenhof, H.P., and Meese, E. Time-resolved RNA signatures of CD4+ T cells in Parkinson's disease. Cell Death Discov 2023; 9:18. doi.org/10.1038/s41420-023-01333-0 Impact Punkte: 6.1.

Karakizlis, H., Agarwal, V., Aly, M., Strecker, K., Csala, B., Esso, I., Chen, J., Nahrgang, C., Wolter, M., Slanina, H., Schuttler, C.G., Jessen, S., Ronco, C., Seeger, W., Weimer, R., Sester, M., Birk, H.W., and Husain-Syed, F. Humoral and cellular immune responses to the mRNA-1273 SARS-CoV-2 vaccine booster in patients on maintenance dialysis. J Nephrol 2023; 36:183-186. doi.org/10.1007/s40620-022-01371-4 Impact Punkte: 2.7.

Hielscher, F., Schmidt, T., Klemis, V., Wilhelm, A., Marx, S., Abu-Omar, A., Ziegler, L., Guckelmus, C., Urschel, R., Sester, U., Widera, M., and Sester, M. Cellular and humoral immunity towards SARS-CoV-2 wildtype and variants of concern after two doses of the NVX-CoV2373 vaccine in comparison to homologous BNT162b and mRNA1273 regimens. J Clin Virol 2022; 157:105321 https://doi.org/10.1016/j.jcv.2022.105321   Impact Punkte: 8.8

Klemis, V., Schmidt, T., Schub, D., Mihm, J., Marx, S., Abu-Omar, A., Ziegler, L., Hielscher, F., Guckelmus, C., Urschel, R., Wagenpfeil, S., Schneitler, S., Becker, S.L., Gärtner, B.C., Sester, U., and Sester, M.
Comparative immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19-priming and BNT162b2 or mRNA-1273-boosting with homologous COVID-19 vaccine regimens.
Nat Commun 2022; 13:4710 Link zum Volltext. Impact Punkte: 16.6.

Schmidt, T., Klemis, V., Schub, D., Schneitler, S., Reichert, M.C., Wilkens, H., Sester, U., Sester, M., and Mihm, J. Cellular immunity predominates over humoral immunity after homologous and heterologous mRNA and vector-based COVID-19 vaccine regimens in solid organ transplant recipients. Am J Transplant 2021; 21:3990-4002. Zugang zum Volltext Impact Punkte: 9.369

Schmidt, T., Klemis, V., Schub, D., Mihm, J., Hielscher, F., Marx, S., Abu-Omar, A., Ziegler, L., Guckelmus, C., Urschel, R., Schneitler, S., Becker, S.L., Gärtner, B.C., Sester, U., and Sester, M. Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination. Nat Med 2021; 27:1530-1535. Zugang zum Volltext Impact Punkte: 87.241.

Simon, A., Reinhardt, T., Meyer, S., Baltaci, Y., Rissland, J., Eichler, H., Klemis, V., Sester, M., and Graf, N. COVID-19 in a pediatric cancer patient with T-lymphoblastic lymphoma: response to convalescence plasma and subsequent induction of SARS-CoV-2 specific humoral and cellular immunity despite strong B-cell lymphopenia. Journal of clinical images and medical case reports 2021; 2.

Gärtner, B.C., and Sester, M. Diversity of antibody responses after influenza infection or vaccination-Needed or nice to have? Am J Transplant 2021; 21:2631-2632. Zugang zum Volltext Impact Punkte: 9.369.

Blumberg, E.A., Manuel, O., Sester, M., and Ison, M.G. The future of SARS-CoV-2 vaccines in transplant recipients: To be determined. Am J Transplant 2021; 21:2629-2630 Zugang zum Volltext Impact Punkte: 9.369.

Danziger-Isakov, L., Blumberg, E., Manuel, O., and Sester, M. Impact of COVID-19 in solid organ transplant recipients. Am J Transplant 2021; 21:925-937. Zugang zum Volltext Impact Punkte: 9.369.

Wiening, V., Schmidt, T., Dahmen, M., Siam, S., Reuter, S., Pavenstädt, H.-J., Sester, M., and Suwelack, B. Management of a multidrug-resistant CMV-strain in a renal transplant recipient by high-dose CMV-specific immunoglobulins, modulation in immunosuppression and induction of CMV-specific cellular immunity – a case report. Frontiers in Immunology 2021;11:623178. Zugang zum Volltext Impact Punkte: 8.786.

Hauser, I.A.*, Marx, S.*, Sommerer, C., Suwelack, B., Dragun, D., Witzke, O., Lehner, F., Schiedel, C., Junge, M., Thaiss, F., Neudörfl, C., Falk, C.S., Nashan, B., and Sester, M. Effect of everolimus-based immunosuppression regimens on cytomegalovirus-specific T-cell functionality after renal transplantation: 12-month results from the ATHENA study. Eur J Immunol 2020; 51:943-955. Zugang zum Volltext Impact Punkte: 6.688. *geteilte Erstautorinnenschaft.

Gupta, R.K., Calderwood, C.J., Yavlinsky, A., Krutikov, M., Quartagno, M., Aichelburg, M.C., Altet, N., Diel, R., Dobler, C.C., Dominguez, J., Doyle, J.S., Erkens, C., Geis, S., Haldar, P., Hauri, A.M., Hermansen, T., Johnston, J.C., Lange, C., Lange, B., van Leth, F., Muñoz, L., Roder, C., Romanowski, K., Roth, D., Sester, M., Sloot, R., Sotgiu, G., Woltmann, G., Yoshiyama, T., Zellweger, J.P., Zenner, D., Aldridge, R.W., Copas, A., Rangaka, M.X., Lipman, M., Noursadeghi, M., and Abubakar, I. Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings. Nat Med 2020; in press. Abstract  Impact Punkte: 53.440.

Schub, D., Klemis, V., Schneitler, S., Mihm, J., Lepper, P.M., Wilkens, H., Bals, R., Eichler, H., Gärtner, B.C., Becker, S.L., Sester, U., Sester, M., and Schmidt, T. High levels of SARS-CoV-2 specific T-cells with restricted functionality in severe course of COVID-19. JCI Insight 2020. in press. Impact Punkte: 8.315. Link zum Volltext

Kos, I., Balensiefer, B., Roth, S., Ahlgrimm, M., Sester, M., Schmidt, T., Thurner, L., Bewarder, M., Bals, R., Lammert, F., Stilgenbauer, S., and Kaddu-Mulindwa, D. Prolonged course of COVID-19-associated pneumonia in a B-cell depleted patient after rituximab. Frontiers in Oncology 2020; in press. Impact Punkte: 6.244. Link zum Volltext

Diener, C., Hart, M., Kehl, T., Rheinheimer, S., Ludwig, N., Krammes, L., Pawusch, S., Lenhof, K., Tänzer, T., Schub, D., Sester, M., Walch-Rückheim, B., Keller, A., Lenhof, H.P., and Meese, E. Quantitative and time-resolved miRNA pattern of early human T cell activation. Nucleic Acids Res 2020; 48:10164-10183. Impact Punkte: 16.971. Abstract

Marx, S., Adam, C., Weyrich, M., Mihm, J., Sester, U., and Sester, M. A polyclonal immune function assay allows dose-dependent characterization of immunosuppressive drug effects but has limited clinical utility for predicting infection on an individual basis. Frontiers in Immunology 2020; Link zum Volltext. Impact Punkte: 7.561.

Abdulnasser Harfoush, S., Hannig, M., Le, D.D., Heck, S., Leitner, M., Omlor, A.J., Tavernaro, I., Kraegeloh, A., Kautenburger, R., Kickelbick, G., Beilhack, A., Bischoff, M., Nguyen, J., Sester, M., Bals, R., and Dinh, Q.T. High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice. Respir Res 2020; 21:168. Impact Punkte: 4.065. Abstract

Stenger, T., Ledo, A., Ziller, C., Schub, D., Schmidt, T., Enders, M., Gärtner, B.C., Sester, M., and Meyer, T. Timing of vaccination after training: Immune response and side effects in athletes. Med Sci Sports Exerc 2020; In press. Impact Punkte: 5.411. Abstract

Ahlenstiel-Grunow, T., Sester, M., Sester, U., Hirsch, H.H., and Pape, L. BK Polyomavirus-specific T Cells as a Diagnostic and Prognostic Marker for BK Polyomavirus Infections After Pediatric Kidney Transplantation. Transplantation 2020; in press. Impact Punkte: 4.939. Abstract

Ledo, A., Schub, D., Ziller, C., Enders, M., Stenger, T., Gärtner, B.C., Schmidt, T., Meyer, T., and Sester, M. Elite athletes on regular training show more pronounced induction of influenza-specific T-cells and antibodies after tetravalent influenza vaccination than controls. Brain Behav Immun 2020; 83:135-145. Impact Punkte: 7.217. Abstract

Zewinger, S., Reiser, J., Jankowski, V., Alansary, D., Hahm, E., Klug, M., Triem, S., Schunk, S.J., Schmit, D., Kramann, R., Körbel, C., Ampofo, E., Laschke, M., Selejan, S.-R., Schuster, S., Silbernagel, G., Sester, M., Sester, U., Assmann, G., Bals, R., Kostner, G., Jahnen-Dechent, W., Menger, M.D., Rohrer, L., März, W., Böhm, M., Jankowski, J., Kopf, M., Latz, E., Niemeyer, B.A., Fliser, D., Laufs, U., and Speer, T. Apolipoprotein C3 induces systemic inflammation and organ damage by alternative inflammasome activation. Nat Immunol 2020; 21:30-41. Impact Punkte: 25.606. Abstract