Interaction of polymer drugs and polymer materials with bacteria and mammalian cells
Projektverantwortliche: Dr. Alice Eickenscheidt
In the context of our SMAMP projects, we study the interaction of polymers and polymer materials with living organisms, such as bacteria and mammalian cells. This includes solution-based assays (determination of the minimum inhibitory concentration for bacterial growth; hemolysis assay to test blood compatibility) as well as assays on materials surfaces (modified JIS Z 2801 assay for antimicrobial activity of materials, AlamarBlue assay for cell compatibility, immunofluorescence assays to study mechanisms of cell adhesion). One current focus is on the interaction of mammalian cells with polyzwitterions.